Lab Members

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Jason S. McLellan, Associate Professor

Jason earned a BS in chemistry with an emphasis in biochemistry from Wayne State University in Detroit, Michigan. Afterward, he obtained his PhD from the Johns Hopkins University School of Medicine in Baltimore, Maryland in the laboratory of Dr. Daniel Leahy. He then carried out postdoctoral research at the National Institutes of Health's Vaccine Research Center in the laboratory of Dr. Peter Kwong and in collaboration with Dr. Barney Graham. In the Fall of 2013, he joined the faculty at the Geisel School of Medicine at Dartmouth in the Department of Biochemistry, and in January 2018 he moved his laboratory to the University of Texas at Austin and became a member of the Department of Molecular Biosciences.

 
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John Ludes-Meyers, Research Associate

John earned his BS in Biochemistry and Biophysics from the University of Minnesota, College of Biological Sciences.  He joined the Genetics graduate program at Texas A&M University in College Station, Texas and earned his Ph.D. in Dr. Van Wilson’s lab focused on structure–function studies of the Bovine Papillomavirus E1 replication protein.  He performed postdoctoral research at the Univ. of Texas Health Science Center in San Antonio investigating the role of mutant p53 and AP-1 transcription factors in carcinogenesis.  John then worked at The Univ. of Texas MD Anderson Cancer Center—Science Park in Smithville, Texas.

 
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Nianshuang Wang, Postdoctoral Scholar

Nianshuang obtained a BS in Biological Sciences from Ocean University of China in 2009. He then joined the Center for Structural Biology in Tsinghua University under Dr. Xinquan Wang's supervision. His research in Tsinghua was focused on the structural mechanism of receptor recognition by MERS-CoV. He earned a PhD in 2014 and subsequently joined the McLellan lab as a postdoc. He will continue to investigate viruses, focusing on the structural basis of viral entry mechanisms and the development of prophylactic and therapeutic interventions.

 

Ching-Lin Hsieh, Postdoctoral Scholar

Ching-Lin received his BS degree in Veterinary Medicine at National Taiwan University where he started to develop his interest in infectious disease. He then earned his MS degree in biochemistry in Academia Sinica. During his PhD studies at Cornell, he began to investigate the pathogenesis of bacterial diseases and developed a potential vaccine candidate using the NMR structure of a surface adhesin. After obtaining his PhD in 2016, he worked on an anti-Fusobacterium vaccine project for colorectal cancer prevention in Dr. Chang’s lab. He is excited to join the McLellan lab as a postdoc where he will investigate viral-host interactions and structure-based vaccine design for viral diseases. (And he is a coffee lover.)

 
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Morgan Gilman, Graduate Student

Morgan earned a BS in Microbiology and an MS in Biochemistry from the University of Maine. She came to Dartmouth in 2012 to work as a technician in the Ackerman laboratory, where her work focused on developing a method for high throughput engineering of HIV vaccine immunogens. She is interested in the structure of viral glycoproteins and understanding the interaction of these proteins with the human immune system.

 
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Harrison Jones, MD/PhD Student

Harrison earned a BS in Chemistry and a minor in History from the University of Utah. He then worked at UCSD's Moores Cancer Center from 2012-2013 assisting in CLL clinical trials and characterizing the efficacy of novel pharmaceuticals. He joined the Geisel MD-PhD program in the fall of 2013 and is interested in pursuing a career that combines academic research with direct patient care.

 
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Daniel Wrapp, Graduate Student

Daniel earned his B.S. in Biological Sciences from the University of Notre Dame in 2015. As a visiting researcher at the Biodesign Institute at Arizona State University, he was involved in the synthesis and evaluation of high-density peptide microarrays used to probe the humoral immune response. He is interested in characterizing host-pathogen interactions by using both structural and biophysical techniques.

 
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Scott Rush, Graduate Student

Scott earned a BS in Biochemistry from the University of Texas at El Paso in 2013. He then went to The University of Texas Medical Branch to complete a post-baccalaureate research education program and stayed on an additional year working as a technician. His work at UTMB used X-ray crystallography and other biophysical techniques to study the interactions of synaptic adhesion molecules in order to better understand their involvement in neurological disorders. He is broadly interested in pathogens and structural biology.

 
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Jory Goldsmith, Graduate Student

Jory earned his BS in Cell and Molecular Biology from Concordia University in Montreal, where he worked on developing mouse genetic models for the study of circadian dysfunction in the brain. He is interested in protein structure and wants to understand how the molecular machines of pathogens function to drive infection.

 
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Akaash Mishra, Graduate Student

Akaash obtained a Bachelor and Master of Technology in Biotechnology from Jaypee Institute of Information Technology in India where he worked on Chikungunya virus envelope protein interactions. He came to the US in 2011 and earned an MS in Biochemistry and Molecular Biology from Indiana University, School of Medicine, where he targeted DNA-protein interactions of nucleotide excision repair proteins for cancer therapy. He then worked as an Associate Scientist at Cook Pharmica LLC for 2.5 years focusing on development of biologics. He is interested in studying the structure of viral glycoproteins and their interactions with the host in order to aid in the development of vaccines and antibody therapeutics.


Lab Alumni

Michael Battles, Graduate Student

Mike received his PhD from the McLellan laboratory in 2018. He then joined Adimab, LLC as a Scientist specializing in antibody discovery. View Mike’s Linkedin Profile here.


Emilie Shipman, Technician

Emilie was a laboratory technician in the McLellan laboratory from 2014-2018. She went on to serve as a technician in the Institute for Biomolecular Targeting at Dartmouth College.